LINXS Event: Welcome to afternoon coffee and a seminar by Prof. Hans J Vogel from University of Calgary
Feb
21
3:00 PM15:00

LINXS Event: Welcome to afternoon coffee and a seminar by Prof. Hans J Vogel from University of Calgary

Hans-Vogel-Picture1.jpg

Prof. Vogel’s research focuses on proteins and peptides that play a role in infectious and inflammatory diseases or in cancer, including calcium-regulatory proteins and host-defense peptides. He is also actively involved in several clinical metabolomic research programs, using NMR spectroscopy and mass spectroscopy to analyse metabolite profiles in patient samples. 

Venue: LINXS Workshop room, Ideon Delta 5, Scheelevägen 19, 5th floor (map)

Time: 15.00 - 16.00 (Coffee and cake is served from 14.45)

Title: Calcium binding to L-plastin regulates actin bundling: a target for new anti-metastasis drugs?


Abstract: The plastin proteins, also known as fimbrins, are found in all eukaryotic organisms, where they are involved in actin-bundling. They have a unique multidomain structure made up of four CH domains and two EF-hand calcium binding motifs. The four CH domains are directly involved in the  bundling of F-actin, while binding of calcium to the EF-hand headpiece of the protein can inhibit this process. Using NMR spectroscopy and various biophysical methods, we have studied the calcium-binding headpiece domains of L-plastin and various other plastics/fimbrins. Our results reveal an unexpected activation mechanism, involving a flexible region in the apo-protein. L-plastin is normally only expressed in white blood cells, but it also is highly expressed in metastatic cancer cells, making this protein a potential target for the development of new anticancer drugs.

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Partner Event: Magnetism, Correlated Systems and X-rays
Mar
14
to Mar 15

Partner Event: Magnetism, Correlated Systems and X-rays

The aim of the workshop, organised by MAX IV and ESS, is to consider how this community can best use MAX IV to study strongly correlated behaviour.

During the workshop, a number of beamlines will present their plans and capabilities for the user community. These beamlines cover both soft and hard X-rays and represent imaging, scattering/diffraction, and spectroscopy techniques. Furthermore, theoretical and experimental experts in the field will share their knowledge and insights to kick-start the formation of new ideas around the use of MAX IV for the study of these solid state phenomena.

Read more and register for the workshop.

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Partner Event: Symposium - Lipid self-assembly - structure, function and applications
Mar
14
2:30 PM14:30

Partner Event: Symposium - Lipid self-assembly - structure, function and applications

Physical Chemistry, Department of Chemistry, Lund University and LINXS (Lund Institute of Advanced Neutron and X-ray Studies) have the pleasure to invite you to this mini-symposium, entitled ”Lipid self-assembly - structure, function and applications”. The focus on the presentations will be on self-assembly structure of biological relevance as revealed neutron and x-ray scattering techniques. Coffee and cake will be served during the symposium.

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Partner Event: Northern Lights on Food
Mar
26
to Mar 27

Partner Event: Northern Lights on Food

Now is the time to create the user community in the food sector that can shape the facilities in terms of access, sample environments and instruments. Together we will discuss how the unique techniques available can contribute to the ongoing and future research in food science and technology.

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Partner Event: French and Swedish School on Energy Materials
May
13
to May 17

Partner Event: French and Swedish School on Energy Materials

– These collaborations are a great way for LINXS to establish its new premises as a vibrant location for workshops and research related events as well as for expanding our network. The presence of the students and lecturers at LINXS at the same time as our working groups will give rise to some very interesting discussions, says Stephen Hall, Director of LINXS.

LINXS is co-organising a French and Swedish School on Energy Materials, together with Swedish and French universities and research organiations. It will focus on the characterisation of materials for the production, processing, storage or transportation of energy that are essential components for current societal challenges.

An important aspect of the school will be to emphasise the complementarity between similar techniques based on one or the other of the radiations, too often ignored. This is because knowledge of structural organization and dynamics at the atomic scale is an essential prerequisite for the study of these materials, and is based, not exclusively but largely, on the use of short-wave radiation, neutrons or X-rays

PhD students and post-doctoral researchers with PhD in physics or chemistry with a mathematical background are welcome to apply to the school.

The school will run between 13-17 May at LINXS in Lund. Registration and more information can be found at: fasem.sciencesconf.org.


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Transdisciplinary imaging at SUBIC - Seminar with Johan Lundström, Director of Stockholm University Brain Imaging Centre
Dec
20
2:30 PM14:30

Transdisciplinary imaging at SUBIC - Seminar with Johan Lundström, Director of Stockholm University Brain Imaging Centre

You are welcome to a seminar given by Johan Lundström, the director of Stockholm University Brain Imaging Centre, Associate Professor at Karolinska Institutet and at the Monell Center/University of Pennsylvania.

Place: LINXS seminar room (Scheelevägen 19, 5th floor)
Time: Thursday Dec 20, at 14:30-15:15 
Title: Transdisciplinary imaging at SUBIC

Stockholm University Brain Imaging Centre (SUBIC) is an advanced multidisciplinary infrastructure dedicated to experimental academic research on brain function and structure. SUBIC is available to all researchers affiliated with Stockholm University or affiliated with other Swedish universities and their international scientific partners.

SUBIC’s infrastructure will support Swedish research with state of the art functional and structural brain imaging technologies suitable for fundamental academic research within the Humanities, Behavioural Sciences, Natural sciences and Law.

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Workshop - Scattering and Dynamics of Flowing Soft Material
Dec
10
to Dec 12

Workshop - Scattering and Dynamics of Flowing Soft Material

The Lund Institute of Advanced Neutron and X-ray Science (LINXS) is organizing its first thematic workshop titled Scattering and Dynamics of Flowing Soft Material. The goal is to bring together leading experts in the field of flows of soft materials, with a particular focus on neutrons and X-rays, but also complementary techniques including NMR, confocal microscopy, theory and computer modeling.  

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The Quantim Hackathon at LINXS!
Nov
26
to Nov 27

The Quantim Hackathon at LINXS!

Scope:
Provide guidance in image analysis and advance the interpretation of complex 3D images in selected scientific cases. Create an environment for cross-fertilization between diverse groups that are in need of similar image quantification tools.

Format:
Users of tomographic instruments and image analysis experts get together to work on 3D image quantification. 1.5 days challenge solving with experts in image analysis, biomedicine and materials.

Time: 12.00 Nov 26 - 14.00 Nov 27

Place: LINXS, Ideon Delta 5, Scheelevägen 19, 5th floor

For more information, please contact: Rajmund Mokso, rajmund.mokso@maxiv.lu.se

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First symposium - Integrative Structural Biology
Nov
19
to Nov 21

First symposium - Integrative Structural Biology

The first symposium, which is the kick-off event for the new LINXS theme, will focus on advanced, cutting-edge research in the fields of macromolecular crystallography, Cryo-EM, small angle scattering, electron diffraction, mass-spectroscopy, NMR, and use of XFELs etc. The target group is primarily from academia but also from several large-scale facilities (MAX IV, ESS, etc) and industry. 

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